How does Propecia cause sexual dysfunction?
Propecia is a medication used for the treatment of male baldness. Propecia contains finasteride. Testosterone is the main androgen in men and is needed for normal sperm, bone, and muscle development in addition to potency and libido. Dihydrotestosterone (DHT) has no physiological role in the adult male but is involved in producing prostate enlargement, balding, and body hair. Merck & Co., the manufacturer of Propecia, discovered that DHT was a causative factor in male pattern baldness.
Finasteride is a type II5-Alpha reductase inhibitor that prevents the conversion of androgen testosterone to DHT. The mechanism of Propecia is quite simple because it inhibits the production of testosterone, a male sex hormone, and so it decreases the problems of elevated testosterone or testosterone sensitivity while creating the same problems as if a man had low testosterone.
Propecia is a brand name for the generic finasteride, a synthetic antiandrogen that prevents enzymes from converting testosterone to (DHT), also called androgen or male sex hormone. In other words, Propecia blocks DHT. It is believed that high levels of DHT are believed to be responsible for hair follicles.
Until recently, it was believed that there were minimal side effects from 5a-reductase inhibitor therapy and also that any side effect was well tolerated. New information suggests that 5a-reductase inhibitor therapy may impair sexual function, sexual desire, and erectile function. Animal research studies suggest that 5a-reductase inhibitors may alter penile tissue and nitric oxide synthase function in penile tissue contributing to erectile dysfunction. Adequate levels of testosterone produced by the testes and an intact pituitary gland are required for the development of a healthy erection. Debilitating sexual side effects including erectile dysfunction, impotency, and loss of libido have been reported following Propecia use. Important to note is that the side effects of Propecia may be long lasting and possibly irreversible.
Propecia attorneys at Oracle Law Group are currently investigating Propecia cases. Oracle Law Group has experienced personal injury attorneys with over 28 years of experience in representing people injured from unsafe products. If you or a loved one has taken Propecia, please contact one of our experienced dangerous drug attorneys for a free consultation.